Tuesday, July 24, 2012

Medical Systems and the holistic approach of applied research


Traditionally in medicine is a longitudinal process, subdivision and phased transfer of knowledge from the generation of basic knowledge to practical application, using the following linear scheme:

Basic Research

Clinical Research

Health Care

For 10 years there has been a paradigm shift in medical science, then cyclical changes in the generation of knowledge and the lack of definitive results of the various ways of understanding the pathophysiology and pathogenic process.

The change has to do with the new concept:

Systems Biology

And

Systems Medicine

The concept of derivative systems Medical Systems Biology states that from a multidisciplinary approach involving external experts agents to medicine, but related to it (biomathematicians, bioinformaticians, bioengineers, etc.), mathematical models must be proposed by complex definition, using anatomico-physiological knowledge from the molecular level to the collective level, and relate to each other to achieve the simulation of organic systems, enabling the intervention on themselves and generate solutions to health problems, both individual and social (collective).

The medicine in this model should be:

1. Participatory

2. Predictive

3. Custom

4. Preventive

It is suggested Linear Stages integrate with each other to establish a two-way interaction model in order to accelerate and ensure the timely application of knowledge, until now late for the solution of problems.

In order to break the traditional model range from basic research to health care, no well-defined stages that would last, in the improved cases, 10 to 15 years, and turn it into a comprehensive model, or an integral do involving basic and applied researchers and those engaged in health care for all the useful knowledge "drain" to the population in the form of improvement in health expectancy.

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